Showing posts with label what causes crohn's disease. Show all posts
Showing posts with label what causes crohn's disease. Show all posts

Tuesday, October 27, 2009

Crohn's Sufferers - Did You Use Accutane?

Thankfully most of my skin problems were a result of Crohn's (THANKS PREDNISONE!), but if you have Crohn's, it could be because you used Accutane. Which also means you could be getting paid large!

Ennis & Ennis, P.A. announces today it is still investigating and accepting Accutane cases against the manufacturer of the drug Hoffman La-Roche. David Ennis states, "although Hoffman La-Roche announced in June 2009 that it will no longer sell Accutane due to generic competition and large legal costs defending the drug this does not absolve La-Roche from liability from patients who took the drug in the past and have suffered Inflammatory Bowel Disease (IBD), Ulcerative Colitis and Crohn’s Disease". Ennis went on to state 6 juries in New Jersey have ruled in favor of plaintiffs in excess of $33,000,000 in damages finding that the company did not adequately warn of the side effects associated with IBD, Ulcerative Colitis and Crohn's Disease. Ennis believes that there are thousands of patients who suffered from these side effects and are not aware it was due to Accutane use.

Ennis & Ennis, P.A. is also investigating and accepting cases against the generic manufacturers of Isotretinoin which is the generic name for Accutane. The generic versions of the drug are Sotret, Claravis and Amnesteem. Ennis states, "The generic drug makers have the same duty to warn as La-Roche, but they have chosen to use the same label as La-Roche which is a head in the sand approach. It is amazing to me that based on the court findings and evidence presented at trial which is now in the public domain the FDA has not stepped in to require a Black Box warning."

Ennis & Ennis, P.A. has been accepting and investigating Accutane cases since 2003. Ennis & Ennis, P.A. continues to offer free legal consultations to all users of Accutane and Isotretinoin that may have developed IBD, Ulcerative Colitis or Crohn’s Disease. Potential victims can call toll-free 1-800-856-6405 or go to http://www.ennislaw.com or http://www.the-accutane-lawyer.com and fill out a free online case evaluation form.

Ennis & Ennis, P.A. is a nationwide law firm with offices in Ft. Lauderdale, Miami and Washington D.C. Ennis & Ennis, P.A. specializes in mass torts and represents individuals against pharmaceutical companies worldwide as well as medical device makers.

Monday, December 17, 2007

The Brits Announce Bacteria in Cows Milk Likely Cause of Crohn's Disease

Scientists at the University of Liverpool, United Kingdom, have discovered a certain type of bacteria in cattle as a likely cause for Crohn's disease in human beings. The bacteria, called Mycobacterium paratuberculosis, are known to cause the debilitating Johne's disease in cattle. It is believed the bacteria are transferred from cows to humans via milk and dairy product consumption. The British scientists have been able to observe reactions caused by the bacteria in the human body that could tap it as a cause for Crohn's disease. This could open up new ways for finding more effective treatment options for Crohn's.
Crohn's disease is a chronic inflammation of the intestines. Patients suffering from Crohn's disease experience pain, bleeding, and diarrhea. If medical treatment options are not successful, relieve can often only be found through the removal of the effected part of the intestines. Similarly, Johne's disease in cattle causes severe diarrhea. As a result of the disease cattle usually slowly perishes. While the cause of Johne's disease has been known, until now there had been no known cause for Crohn's disease. It has been most recently theorized that Crohn's (not Chrones, chrons, or chron's) disease is genetically linked. The British Scientists now seem to be able to explain how the presence of Mycobacterium paratuberculosis in a patient's body can cause Crohn's disease.
It has long been known that patients suffering from Crohn's disease have a higher than usual level of E.coli bacteria in their body. Similarly, Mycobacterium paratuberculosis has been known to be present in Crohn's disease tissue. But until now, nobody has been able to explain the bacteria's presence and connection to the disease. Now the British scientists have been able to observe that the bacteria, Mycobacterium paratuberculosis, inhibit the body's immune system response to E.coli bacteria.
Mycobacterium paratuberculosis discharges a mannose-containing molecule. Mannose is a type of sugar. This molecule stops macrophages, a type of white blood cells, from destroying E.coli bacteria in the patient's body. The increased level of E.coli bacteria weakens the immune systems response to other intestinal bacteria, including Mycobacterium paratuberculosis.
The scientists also determined that the bacteria could cause an increase in a circulating antibody protein (ASCA). Two-thirds of Crohn's disease patients have this type of protein indicating a likely infection with Mycobacterium paratuberculosis.
Clinical trials are planned to seek out treatment options through an antibiotic combination, which is aimed at eliminating Mycobacterium paratuberculosis in a Crohn's disease patient's body. If the scientists' assumption is correct, the disease should subside with the elimination of the bacteria.

Crohn's Disease Blog